Class A Credits: 1
Pharmacology Credits: 0.5
Course Launch Date: 12/15/22
Course Expires: 12/14/23
Recent studies have shown that many pain management and anesthesia providers are optimistic about the role of precision health in pain management, but are uncertain about practical aspects of testing and desire clear guidelines on the use of results.
We have developed a better understanding of cellular and molecular mechanisms that link neuroinflammatory processes, dysfunctional sensitization, and pain in recent years. In addition, we have learned that environmental exposures and genetic predisposition are associated with various chronic pain conditions. Despite our better understanding, up to 85% of patients still experience moderate to severe pain after surgery, and about 30 to 50% of patients develop chronic pain postoperatively. Both genetic and environmental factors influence patients’ response to opioid pain medications. Today, pharmacogenomics and pharmaco-epigenetic can assist in addressing the ambitious queries related to interindividual variations in response to pain medications.
Much has been written about pharmacogenomics and pharmaco-epigenomics and response to opioid pain medications. Several experts have assembled guidelines to integrate this knowledge into practice. This presentation aims to discuss the contribution of genetic and epigenetic differences in patients’ responses to opioid medications, using the following questions to assist CRNAs in caring for patients.
1) What are Pharmacogenomics and pharmaco-epigenomics?
2) When should a pharmacogenomic test be ordered?
3) Should a single gene test or panel of genes be ordered?
4) How will the results be reported?
5) What are some additional clinical considerations for managing patients with pain?
The American Association of Nurse Anesthesiology is accredited as a provider of continuing nursing education by the American Nurses Credentialing Center's Commission on Accreditation.
AANA is an approved provider by the California Board of Registered Nursing, CEP #10862.
Post-Test Attempt Notice
A minimum passing score of 80% is required to pass this course. You have TWO opportunities to achieve a passing score. If you fail to achieve a passing score of 80%, you will not receive CE credit for this course.
The views, information, or opinions expressed within the videos and audio are solely those of the individuals involved and do not necessarily represent those of the American Association of Nurse Anesthesiology.
Course content has been prepared by the presenter/developer, and each viewer agrees that the presenter/developer is solely responsible for the content and the accuracy thereof. The viewer agrees that the American Association of Nurse Anesthesiology has no responsibility or liability for the accuracy or completeness of the content.
All presenters and planners of this CNE activity are required to disclose to the audience any significant financial relationship with the manufacturer(s) of any commercial products, goods, or services related to patient care. If any conflict has been disclosed, the planners of this program assure that the content is unbiased and free of any conflicts of interest. All planners, authors, and content reviewers disclosed there were no commercial interest relationships to declare.
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