AANA June 2022 Journal Course: Demystifying Buprenorphine with Current Evidence-Based Practice in Acute and Chronic Pain Management (ME)

Start Course Now

Class A Credits: 1

Format: Video

Course Launch Date: 6/7/22

Course Expires: 6/6/25

Buprenorphine has been widely used in opioid Medication Assisted Treatment (MAT) in the last decade. However, due to misinterpretation of its intrinsic mu opioid receptor activity extrapolated from preclinical and animal data, buprenorphine's clinical application in pain management has been greatly limited. Buprenorphine acts as a full mu agonist with fewer side effects compared to traditional opioids and can be effectively used in the treatment of acute and chronic pain. A strong body of evidence demonstrates that buprenorphine is an effective analgesic agent in both adult and pediatric surgical patients. In addition, buprenorphine has been successfully used in treating chronic pain, particularly in cancer pain and neuropathic pain. In this journal course, buprenorphine's receptor pharmacology and pharmacokinetics are reviewed. Specifically, misinterpretation of its intrinsic mu receptor activity, and both analgesic ceiling effect and efficacy are clarified. Differences between Suboxone and buprenorphine, and specific applications are explained. Pain management options and guidelines for surgical patients on buprenorphine are discussed as well.

The American Association of Nurse Anesthesiology is accredited as a provider of continuing nursing education by the American Nurses Credentialing Center's Commission on Accreditation.

AANA is an approved provider by the California Board of Registered Nursing, CEP #10862.

Post-Test Attempt Notice
A minimum passing score of 80% is required to pass this course. You have TWO opportunities to achieve a passing score. If you fail to achieve a passing score of 80%, you will not receive CE credit for this course.

Content Disclaimer:

The views, information, or opinions expressed within the videos and audio are solely those of the individuals involved and do not necessarily represent those of the American Association of Nurse Anesthesiology.

Course content has been prepared by the presenter/developer, and each viewer agrees that the presenter/developer is solely responsible for the content and the accuracy thereof. The viewer agrees that the American Association of Nurse Anesthesiology has no responsibility or liability for the accuracy or completeness of the content.

Disclosure Statement:

All presenters and planners of this CNE activity are required to disclose to the audience any significant financial relationship with the manufacturer(s) of any commercial products, goods, or services related to patient care. If any conflict has been disclosed, the planners of this program assure that the content is unbiased and free of any conflicts of interest. All planners, authors, and content reviewers disclosed there were no commercial interest relationships to declare.

  • Demonstrate an understanding of buprenorphines receptor pharmacology and analgesic efficacy compared to other opioids.
  • Discuss the current evidencebased practice with the use of buprenorphine in acute and chronic pain management.
  • Compare the differences between buprenorphine and Suboxone.
  • Identify the current recommendations for surgical patients who are on buprenorphine.

Abby, Niedermann Stewart


Abby Niedermann Stewart, BSN, RN is a rising third-year student in Duke University's DNP Nurse Anesthesia Program. Abby obtained her BSN at the University of Central Florida Orlando, Florida. Prior to entering the Nurse Anesthesia Program, she worked in an Emergency Department, as a Neonatal RN in a Labor/Obstetrics department, and in a Cardiovascular Recovery ICU. As a student, Abby serves as the Class of 2022 Representative and Fundraising Chair. She has volunteered for program interview days, new student orientation, and has assisted in the ultrasound and cadaver labs. In addition to her doctoral project concerning data transparency policy, she participates in a team exploring anatomic variations of of the brachial plexus using ultrasound.

Sarah Zhang, CRNA, PhD

Assistant Professor Samuel Merritt University

Sarah Jingying Zhang is a senior nurse anesthetist working in the department of anesthesiology at UCSF. She is also an adjunct assistant professor at Samuel Merritt University. Prior to becoming a CRNA, she completed her Master and PhD degree in Biomedical Engineering at Duke University. She continued her research training as a post-doctoral fellow at Stanford University and followed by UCSF/VA hospital. She has multiple publications in top peer reviewed journals and presented her research at several national biomedical science conferences. She also serves as a reviewer of American Association of Nurse Anesthetist. Currently she is working on two prospective clinical trials at UCSF.